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Trazodone and Breastfeeding

What is and isn't known about trazodone use while breastfeeding, and how to approach the decision.

Editorially reviewed
Key points
  • Breastfeeding-specific data is more limited than for some alternatives
  • Not the same as being known to be unsafe — just less studied
  • Involve both your prescriber and your baby's pediatrician in the decision

Comprehensive breastfeeding-specific safety data for trazodone is more limited compared with some other antidepressants that have been more extensively studied in lactation. This doesn't mean it's known to be unsafe — it means the evidence base is thinner, which calls for an individualized conversation rather than a blanket answer.

If you're breastfeeding and trazodone is being considered or continued, discuss it with both your prescriber and your baby's pediatrician, who can weigh your specific treatment needs, dose, and any observations about your infant.

References

  1. Trazodone: MedlinePlus Drug Information. U.S. National Library of Medicine (MedlinePlus). View source (opens in a new tab) Accessed August 8, 2026
  2. Trazodone Hydrochloride Tablets — FDA Prescribing Information. DailyMed / U.S. Food & Drug Administration. View source (opens in a new tab) Accessed August 8, 2026
Not medical advice. This article is educational and does not replace guidance from your prescriber or pharmacist. If you think you're having a serious reaction, see our emergency resources page.

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