Trazodone's side effects span a wide range of severity. Common, usually mild effects include drowsiness, dizziness, dry mouth, headache, and nausea. Less common effects include tremor, confusion, and changes in taste. More serious effects include significant blood pressure drops and unusual bruising or bleeding.
At the most serious end, trazodone's FDA labeling specifically warns about priapism, serotonin syndrome, QT prolongation/irregular heartbeat, hyponatremia, and — as an antidepressant-class warning — suicidal thoughts in younger patients. Explore our full Side-Effect Library for a detailed page on each.