Desyrel was the original brand name under which trazodone was marketed after its 1981 FDA approval. Generic versions, made by multiple manufacturers, must meet FDA bioequivalence standards, meaning they deliver the same active ingredient at the same rate and extent as the brand product. Nearly all trazodone dispensed in the U.S. today is generic.
Is generic trazodone the same as brand-name Desyrel?
Short answer: Yes. Generic trazodone hydrochloride is FDA-reviewed as therapeutically equivalent to the original brand-name product, and is what the vast majority of prescriptions dispense today.
Editorially reviewed
Not medical advice. This answer is general and educational. Your prescriber knows your full history and can give guidance specific to you.