According to trazodone's current prescribing information, published cohort studies, case series, and case reports over several decades have not identified clear drug-associated risks of major birth defects or adverse pregnancy outcomes in humans, though data remains more limited than for some other medications. Animal studies at doses far above typical human doses showed some effects. Any decision about taking trazodone during pregnancy should be made individually with your prescriber, weighing your specific health needs.
Is trazodone safe during pregnancy?
Short answer: Data is limited but has not identified a clear pattern of major birth defect risk in available studies; it is generally used in pregnancy only when the potential benefit outweighs potential risks, decided with your prescriber.
Editorially reviewed
Not medical advice. This answer is general and educational. Your prescriber knows your full history and can give guidance specific to you.