Not medical advice. General education only — not medical advice, and not a substitute for your prescriber or pharmacist. Emergency & crisis resources · How we review content

Why does my trazodone prescription come with a Medication Guide?

Short answer: The FDA requires a Medication Guide for trazodone because of its boxed warning and other significant risks that patients specifically need to understand — pharmacies must provide it with each dispensing.

Editorially reviewed

FDA-required Medication Guides accompany certain medications with risks the FDA has determined patients need direct, plain-language information about. For trazodone, this covers the suicidality boxed warning, serotonin syndrome, priapism, and other serious risks. Reading it is worthwhile even if your prescriber has already discussed these points with you.

Not medical advice. This answer is general and educational. Your prescriber knows your full history and can give guidance specific to you.

Keep track of your own experience

The Medication Companion lets you log doses, sleep, symptoms, and questions for your prescriber — privately, in your browser, no account required to start.

Open the Medication Companion