Trazodone Side-Effect Library
Real descriptions of what each side effect feels like in practice, how common it is, and clear guidance on when to just monitor it versus when to call your prescriber or seek urgent care.
Significant drops in blood pressure on standing
When mild dizziness on standing progresses to near-fainting or fainting, it becomes a serious safety issue, particularly for older adults an…
Read more → CommonSwelling (edema)
Listed among trazodone's common side effects in current FDA labeling, typically involving mild fluid retention.
Read more → Less commonTremor (shakiness)
A less commonly reported neurological side effect involving fine shakiness, usually in the hands.
Read more → SeriousTriggering mania or hypomania
Like other antidepressants, trazodone can occasionally unmask or trigger manic or hypomanic symptoms, particularly in people with undiagnose…
Read more → SeriousUnusual bruising or bleeding
Serotonergic antidepressants, including trazodone, can affect platelet function, occasionally leading to increased bruising or bleeding.
Read more → Less commonVivid or unusual dreams
Some people using trazodone for sleep report more vivid or unusual dreams, likely related to its effect on sleep architecture.
Read more → CommonWeight changes
Trazodone's label lists weight loss among common effects, though individual experience varies and some people report the opposite.
Read more → EmergencyWorsening depression or suicidal thoughts
The subject of trazodone's FDA boxed warning: antidepressants, including trazodone, can increase suicidal thinking in children, adolescents,…
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