Respiratory arrest is listed among the most severe reactions reported with trazodone overdose, particularly when combined with other CNS-depressing substances.
Respiratory arrest — a complete stop in breathing — is listed in trazodone's prescribing information among the most severe reactions reported in overdose. This risk rises sharply when trazodone is combined with alcohol, opioids, benzodiazepines, or other substances that also suppress breathing and the central nervous system.
Call 911 immediately for any suspected overdose or serious breathing difficulty, and contact Poison Control at 1-800-222-1222 for guidance.
A drop in blood sodium levels that can become severe, causing confusion, seizures, or worse if untreated — listed directly in trazodone's FD…
Read more →The subject of trazodone's FDA boxed warning: antidepressants, including trazodone, can increase suicidal thinking in children, adolescents,…
Read more →Seizures are listed among the most severe reactions reported with trazodone overdose, and are a medical emergency wherever they occur.
Read more →Trazodone can affect the heart's electrical rhythm in a way that, in rare cases, leads to a dangerous or fainting-inducing arrhythmia.
Read more →The Medication Companion lets you log doses, sleep, symptoms, and questions for your prescriber — privately, in your browser, no account required to start.