A common, usually mild anticholinergic-type effect that can be managed with hydration and sugar-free lozenges.
Dry mouth is one of the more universally reported antidepressant side effects, and trazodone is no exception, although its anticholinergic burden is milder than older tricyclic antidepressants like amitriptyline.
Sipping water, chewing sugar-free gum, or using saliva-substitute products can help. Persistent dry mouth can also increase dental cavity risk over time, so mentioning it to a dentist is reasonable if it continues for months.
Distinct from acute drowsiness, this is a lingering sense of low energy some people notice, especially early in treatment.
Read more →A commonly reported, minor side effect specifically listed in trazodone's FDA labeling.
Read more →Trazodone's label lists weight loss among common effects, though individual experience varies and some people report the opposite.
Read more →Listed among trazodone's common side effects in current FDA labeling, typically involving mild fluid retention.
Read more →The Medication Companion lets you log doses, sleep, symptoms, and questions for your prescriber — privately, in your browser, no account required to start.